{"id":17266,"date":"2020-05-02T08:05:38","date_gmt":"2020-05-02T05:05:38","guid":{"rendered":"https:\/\/xenobg.com\/?p=17266"},"modified":"2020-05-09T09:36:56","modified_gmt":"2020-05-09T06:36:56","slug":"podcast-epizod-6","status":"publish","type":"post","link":"https:\/\/xenobg.com\/el\/podcast-epizod-6\/","title":{"rendered":"\u0414\u043e\u043f\u044a\u043b\u043d\u0438\u0442\u0435\u043b\u043d\u0430 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f \u043a\u044a\u043c \u0415\u043f\u0438\u0437\u043e\u0434 6 \u043d\u0430 \u043f\u043e\u0434\u043a\u0430\u0441\u0442"},"content":{"rendered":"\n<figure class=\"wp-block-embed-youtube wp-block-embed is-type-video is-provider-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"[\u0415\u041f.6] \u0413\u0435\u043e\u0440\u0433\u0438 \u0414\u0438\u043d\u043a\u043e\u0432(Haidut) -\u0437\u0430 \u0434\u0438\u0430\u0431\u0435\u0442\u0430 \u0438 \u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0432\u0430\u0442\u0430 \u0440\u0435\u0437\u0438\u0441\u0442\u0435\u043d\u0442\u043d\u043e\u0441\u0442\" width=\"1080\" height=\"608\" src=\"https:\/\/www.youtube.com\/embed\/e_OxeTCw6J8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>\u0414\u043e\u043a\u0443\u043c\u0435\u043d\u0442\u0438 \u0437\u0430 \u0410\u0446\u0438\u043f\u0430\u043c\u043e\u043a\u0441<\/p>\n\n\n\n<p><a href=\"https:\/\/en.wikipedia.org\/wiki\/Acipimox\">https:\/\/en.wikipedia.org\/wiki\/Acipimox<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8306591\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8306591<\/a><\/p>\n\n\n\n<p>&#8222;&#8230;After 3 days of acipimox treatment, fasting and 24-h plasma glucose and serum triglyceride concentrations were significantly reduced (p &lt; 0.05), but no longer after 4 weeks of treatment. Despite the rebound rise in NEFA, acute administration of acipimox still inhibited both oxidative and non-oxidative NEFA metabolism in the basal state (p &lt; 0.01-0.001) and during insulin infusion (p &lt; 0.05-0.001). Inhibition of NEFA metabolism was associated with increased insulin-stimulated glucose uptake (from 3.56 +\/- 0.28 to 5.14 +\/- 0.67 mumol kg-1 min-1, p &lt; 0.05), mainly due to stimulation of non-oxidative glucose disposal (from 1.74 +\/- 0.23 to 3.03 +\/- 0.53 mumol kg-1 min-1, p &lt; 0.05). In conclusion, acipimox administered acutely inhibits NEFA appearance (lipolysis), which is associated with improved glucose uptake.&#8220;<\/p>\n\n\n\n<p><a href=\"https:\/\/dm5migu4zj3pb.cloudfront.net\/manuscripts\/115000\/115432\/cache\/115432.1-20150302164831-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf\">https:\/\/dm5migu4zj3pb.cloudfront.net\/manuscripts\/115000\/115432\/cache\/115432.1-20150302164831-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf<\/a><\/p>\n\n\n\n<p>&#8222;&#8230;Acipimox increased glucose oxidation in the basal state (76 +\/- 4 vs. 50 +\/- 4 mg\/m2<\/p>\n\n\n\n<p>per min, P less than 0.01). During insulin infusion Acipimox increased both glucose<\/p>\n\n\n\n<p>oxidation (121 +\/- 7 vs. 95 +\/- 4 mg\/m2 per min, P less than 0.01) and nonoxidative glucose<\/p>\n\n\n\n<p>disposal (248 [\u2026]&#8220;<\/p>\n\n\n\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1007\/BF00580753\">https:\/\/link.springer.com\/article\/10.1007\/BF00580753<\/a><\/p>\n\n\n\n<p>&#8222;&#8230;Acipimox decreased basal NEFA concentrations (P&lt;0.01) and reduced lipid oxidation during low-dose insulin infusion (P&lt;0.05). Glucose uptake, predominantly glycogen formation, was stimulated by acipimox (P&lt;0.05). In conclusion, the insulin resistance of glucose metabolism associated with hypertriglyceridaemia is largely due to a defect in non-oxidative glucose metabolism. Acipimox improves glucose metabolism both by affecting glucose oxidation (low-dose insulin) and non-oxidative glucose metabolism (high-dose insulin).&#8220;<\/p>\n\n\n\n<p>Randle Cycle \u043a\u043e\u0439\u0442\u043e \u043f\u043e\u043a\u0430\u0437\u0432\u0430, \u0447\u0435 \u043c\u043e\u0436\u0435 \u0438\u043b\u0438 \u0441\u0430\u043c\u043e \u043c\u0430\u0437\u043d\u0438\u043d\u0430 \u0438\u043b\u0438 \u0437\u0430\u0445\u0430\u0440 \u0434\u0430 \u0441\u0435 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u0438\u0440\u0430 \u043e\u0442 \u043a\u043b\u0435\u0442\u043a\u0430\u0442\u0430 \u0432 \u0434\u0430\u0434\u0435\u043d \u043c\u043e\u043c\u0435\u043d\u0442.<\/p>\n\n\n\n<p><a href=\"https:\/\/en.wikipedia.org\/wiki\/Randle_cycle\">https:\/\/en.wikipedia.org\/wiki\/Randle_cycle<\/a><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>\u0430\u043b\u043a\u043e\u0445\u043e\u043b\u043d\u0438\u044f \u043a\u043e\u043a\u0442\u0435\u0439\u043b &#8222;\u041a\u043e\u043d\u0442\u0435\u0441\u0430\u0442\u0430&#8220; \u0438\u043b\u0438 &#8222;\u0414\u044e\u043a\u0435\u0441\u0430\u0442\u0430&#8220; \u0437\u0430 \u0440\u0443\u0441\u043a\u0438\u0442\u0435 \u043e\u043b\u0438\u043c\u043f\u0438\u0439\u0446\u0438:<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><a href=\"https:\/\/www.businessinsider.com\/russia-drugs-sochi-athletes-performance-2016-5\">https:\/\/www.businessinsider.com\/russia-drugs-sochi-athletes-performance-2016-5<\/a><\/p>\n\n\n\n<p>&#8222;&#8230;Rodchenkov said his formula was exact: For very milliliter of alcohol, he used one milligram of the steroid blend. Rather than just downing the mixture, which would delay the absorption of the drugs until they could crossed the barrier of the stomach, the athletes &#8222;were instructed to swish the liquid around in their mouths, under the tongue,&#8220; The Times reported.&#8220;<\/p>\n\n\n\n<p>\u0412\u0438\u0436 \u043f\u043e\u0441\u043b\u0435\u0434\u043d\u043e\u0442\u043e \u0438\u0437\u0440\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u0446\u0438\u0442\u0430\u0442\u0430. \u0422\u0430\u043c \u043f\u0438\u0448\u0435 \u0447\u0435 \u0441\u0435 \u0434\u044a\u0440\u0436\u0438 \u043f\u043e\u0434 \u0435\u0437\u0438\u043a\u0430, \u043a\u0430\u043a\u0442\u043e \u0438 \u043d\u0430\u0449\u0435 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438.<\/p>\n\n\n\n<p>\u0415\u0442\u043e \u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0430:<\/p>\n\n\n\n<p>&#8222;&#8230;Russian athletes took home 33 medals at the Sochi games, including 13 golds. One-third of them were awarded to athletes who are now being accused of receiving Rodchenkov&#8217;s cocktail. According to The Times, the names of these athletes are included on a spreadsheet outlining the doping plan that Rodchenkov said was given to him by the Russian government sports ministry.&#8220;<\/p>\n\n\n\n<p>\u0417\u0430 \u043b\u0438\u043f\u043e\u043b\u0438\u0437 \u0438 \u0434\u0438\u0430\u0431\u0435\u0442\u0430:<\/p>\n\n\n\n<p><a href=\"https:\/\/link.springer.com\/article\/10.1007\/BF01213565\">https:\/\/link.springer.com\/article\/10.1007\/BF01213565<\/a><\/p>\n\n\n\n<p>&#8222;&#8230;High plasma levels of free fatty acids decrease glucose utilization of muscle and the effects of insulin thereon. Therefore, pharmacologic inhibition of lipolysis has been investigated in order to find new and better ways to adjust the metabolic situation in diabetes mellitus. We have used 5-methylpyrazole-3-carboxylic acid as a model antilipolytic compound. This drug, nicotinic acid and prostaglandin E1 not only inhibit lipolysis, but they also markedly enhance glucose uptake of adipose tissuein vivo. 5-methylpyrazole-3-carboxylic acid prevents the rise of the free fatty acids and of blood glucose acutely after the administration of anti-insulin serum. &#8222;<\/p>\n\n\n\n<p>\u0410\u0441\u043f\u0438\u0440\u0438\u043d \u0437\u0430 \u0414\u0438\u0430\u0431\u0435\u0442<\/p>\n\n\n\n<p><a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/27\/7\/750\">https:\/\/diabetes.diabetesjournals.org\/content\/27\/7\/750<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/academic.oup.com\/jcem\/article\/93\/7\/2523\/2598525\">https:\/\/academic.oup.com\/jcem\/article\/93\/7\/2523\/2598525<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/journals.sagepub.com\/doi\/10.1345\/aph.1M483\">https:\/\/journals.sagepub.com\/doi\/10.1345\/aph.1M483<\/a><\/p>\n\n\n\n<p>\u041d\u0438\u043a\u043e\u0442\u0438\u043d\u0430\u043c\u0438\u0434 \u0437\u0430 \u0414\u0438\u0430\u0431\u0435\u0442(\u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0437\u0430\u0432\u0438\u0441\u0438\u043c)<\/p>\n\n\n\n<p><a href=\"http:\/\/journal.diabetes.org\/diabetescare\/FullText\/Supplements\/DiabetesCare\/Supplement299\/B16.asp\">http:\/\/journal.diabetes.org\/diabetescare\/FullText\/Supplements\/DiabetesCare\/Supplement299\/B16.asp<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/31\/9\/749\">https:\/\/diabetes.diabetesjournals.org\/content\/31\/9\/749<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/lpi.oregonstate.edu\/book\/export\/html\/80#type-1-diabetes-prevention\">https:\/\/lpi.oregonstate.edu\/book\/export\/html\/80#type-1-diabetes-prevention<\/a><\/p>\n\n\n\n<p>\u043d\u0438\u043a\u043e\u0442\u0438\u043d\u0430\u043c\u0438\u0434\u0437\u0430 \u0434\u0438\u0430\u0431\u0435\u0442 \u0442\u0438\u043f 2<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24314867\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24314867<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24314867\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24314867<\/a><\/p>\n\n\n\n<p>\u0435\u0442\u043e \u0430 \u0441\u0442\u0430\u0442\u0438\u044f\u0442\u0430 \u043e\u0442 1858 \u0433\u043e\u0434\u0438\u043d\u0430, \u043a\u043e\u044f\u0442\u043e \u043f\u043e\u043a\u0430\u0437\u0432\u0430 \u0447\u0435 \u0441\u044a\u0441 \u0437\u0430\u0445\u0430\u0440 \u043c\u043e\u0436\u0435 \u0434\u0430 \u0441\u0435 \u043b\u0435\u043a\u0443\u0432\u0430 \u0434\u0438\u0430\u0431\u0435\u0442.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.jstor.org\/stable\/25192136?seq=1#metadata_info_tab_contents\">https:\/\/www.jstor.org\/stable\/25192136?seq=1#metadata_info_tab_contents<\/a><\/p>\n\n\n\n<p>\u043f\u043e\u0447\u0432\u0430\u0442 \u043e\u0442 \u0432\u0442\u043e\u0440\u0430\u0442\u0430 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430 \u0438 \u0441\u0435 \u043a\u0430\u0437\u0432\u0430 &nbsp;&#8222;Sugar and Diabetes&#8220;.<\/p>\n\n\n\n<p>\u0438 \u0435\u0442\u043e 3 \u0441\u0442\u0430\u0442\u0438\u0438, \u043a\u043e\u0438\u0442\u043e \u043f\u043e\u043a\u0430\u0437\u0432\u0430\u0442 \u0447\u0435 \u043c\u0430\u0437\u043d\u0438\u043d\u0438\u0442\u0435 \u0432 \u043a\u0440\u044a\u0432\u0442\u0430 \u0438\u043c\u0430\u0442 \u0442\u043e\u043a\u0441\u0438\u0447\u0435\u043d \u0435\u0444\u0435\u043a\u0442 \u0432\u044a\u0440\u0445\u0443 \u043f\u0430\u043d\u043a\u0440\u0435\u0430\u0441\u0430.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4063119\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4063119\/<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/51\/suppl_1\/S134\">https:\/\/diabetes.diabetesjournals.org\/content\/51\/suppl_1\/S134<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/51\/5\/1437\">https:\/\/diabetes.diabetesjournals.org\/content\/51\/5\/1437<\/a><\/p>\n\n\n\n<p>\u0438 \u043f\u043e\u0441\u043b\u0435\u0434\u043d\u043e \u0438 \u043c\u043e\u0436\u0435 \u0431\u0438 \u043d\u0430\u0439-\u0432\u0430\u0436\u043d\u043e \u0435 \u0447\u0435 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430 \u043a\u043e\u0438\u0442\u043e \u043d\u0430\u043c\u0430\u043b\u044f\u0432\u0430\u0442 \u043a\u0440\u044a\u0432\u043d\u0430\u0442\u0430 \u0437\u0430\u0445\u0430\u0440 \u0443\u0432\u0435\u043b\u0438\u0447\u0430\u0432\u0430\u0442 \u0440\u0438\u0441\u043a\u043e\u0432\u0435\u0442\u0435 \u0437\u0430 \u0443\u043c\u0438\u0440\u0430\u043d\u0435 \u043e\u0442 \u0432\u0441\u044f\u043a\u0430\u043a\u0432\u0438 \u043f\u0440\u0438\u0447\u0438\u043d\u0438.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.pharmaceutical-journal.com\/news-and-analysis\/study-claims-low-hba1c-increases-mortality-risk\/10994510.article?firstPass=false\">https:\/\/www.pharmaceutical-journal.com\/news-and-analysis\/study-claims-low-hba1c-increases-mortality-risk\/10994510.article?firstPass=false<\/a><\/p>\n\n\n\n<p>3 \u043b\u0438\u043d\u043a\u0430 \u0437\u0430  beta-hydroxybutyrate i acetoacetate.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3058661\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3058661\/<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18184896\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18184896<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/diabetes.diabetesjournals.org\/content\/20\/7\/485\">https:\/\/diabetes.diabetesjournals.org\/content\/20\/7\/485<\/a><\/p>\n\n\n<div data-block-name=\"woocommerce\/handpicked-products\" data-columns=\"1\" data-content-visibility=\"{&quot;title&quot;:true,&quot;price&quot;:true,&quot;rating&quot;:false,&quot;button&quot;:true}\" data-edit-mode=\"false\" data-products=\"[17163]\" class=\"wc-block-grid wp-block-handpicked-products wp-block-woocommerce-handpicked-products wc-block-handpicked-products has-1-columns has-multiple-rows\"><ul class=\"wc-block-grid__products\"><li class=\"wc-block-grid__product\">\n\t\t\t\t<a href=\"https:\/\/xenobg.com\/el\/produkt\/niacinamide\/\" class=\"wc-block-grid__product-link\">\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"wc-block-grid__product-image\"><img decoding=\"async\" width=\"450\" height=\"450\" src=\"https:\/\/xenobg.com\/wp-content\/uploads\/2020\/03\/niacinamide-vitamin-b3-drops-450x450.webp\" class=\"attachment-woocommerce_thumbnail size-woocommerce_thumbnail\" alt=\"Niacinamide vitamin b3 liquid 30ml\" \/><\/div>\n\t\t\t\t\t<div class=\"wc-block-grid__product-title\">\u041d\u0438\u0430\u0446\u0438\u043d\u0430\u043c\u0438\u0434 &#8211; \u0432\u0438\u0442\u0430\u043c\u0438\u043d \u04123 100% \u0443\u0441\u0432\u043e\u0438\u043c<\/div>\n\t\t\t\t<\/a>\n\t\t\t\t<div class=\"wc-block-grid__product-price price\"><span class=\"woocommerce-Price-amount amount\">15.00<span class=\"woocommerce-Price-currencySymbol\">&euro;<\/span><\/span><\/div>\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-button wc-block-grid__product-add-to-cart\"><a href=\"\/el\/wp-json\/wp\/v2\/posts\/17266?add-to-cart=17163\" aria-label=\"\u03a0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c3\u03c4\u03bf \u03ba\u03b1\u03bb\u03ac\u03b8\u03b9: &ldquo;\u041d\u0438\u0430\u0446\u0438\u043d\u0430\u043c\u0438\u0434 - \u0432\u0438\u0442\u0430\u043c\u0438\u043d \u04123 100% \u0443\u0441\u0432\u043e\u0438\u043c&rdquo;\" data-quantity=\"1\" data-product_id=\"17163\" data-product_sku=\"\" data-price=\"15\" rel=\"nofollow\" class=\"wp-block-button__link  add_to_cart_button ajax_add_to_cart\">\u03a0\u03c1\u03bf\u03c3\u03b8\u03ae\u03ba\u03b7 \u03c3\u03c4\u03bf \u03ba\u03b1\u03bb\u03ac\u03b8\u03b9<\/a><\/div>\n\t\t\t<\/li><\/ul><\/div>","protected":false},"excerpt":{"rendered":"<p>\u0414\u043e\u043a\u0443\u043c\u0435\u043d\u0442\u0438 \u0437\u0430 \u0410\u0446\u0438\u043f\u0430\u043c\u043e\u043a\u0441 https:\/\/en.wikipedia.org\/wiki\/Acipimox https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8306591 &#8222;&#8230;After 3 days of acipimox treatment, fasting and 24-h plasma glucose and serum triglyceride concentrations were significantly reduced (p &lt; 0.05), but no longer after 4 weeks of treatment. Despite the rebound rise in NEFA, acute administration of acipimox still inhibited both oxidative and non-oxidative NEFA metabolism in the basal [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1020],"tags":[1032],"class_list":["post-17266","post","type-post","status-publish","format-standard","hentry","category-1020","tag-1032"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u0414\u043e\u043f\u044a\u043b\u043d\u0438\u0442\u0435\u043b\u043d\u0430 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f \u043a\u044a\u043c \u0415\u043f\u0438\u0437\u043e\u0434 6 \u043d\u0430 \u043f\u043e\u0434\u043a\u0430\u0441\u0442 - \u0423\u0441\u0435\u0442\u0438, \u043c\u0438\u0441\u043b\u0438, \u0434\u0435\u0439\u0441\u0442\u0432\u0430\u0439<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/xenobg.com\/el\/podcast-epizod-6\/\" \/>\n<meta property=\"og:locale\" content=\"el_GR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0414\u043e\u043f\u044a\u043b\u043d\u0438\u0442\u0435\u043b\u043d\u0430 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f \u043a\u044a\u043c \u0415\u043f\u0438\u0437\u043e\u0434 6 \u043d\u0430 \u043f\u043e\u0434\u043a\u0430\u0441\u0442 - \u0423\u0441\u0435\u0442\u0438, \u043c\u0438\u0441\u043b\u0438, \u0434\u0435\u0439\u0441\u0442\u0432\u0430\u0439\" \/>\n<meta property=\"og:description\" content=\"\u0414\u043e\u043a\u0443\u043c\u0435\u043d\u0442\u0438 \u0437\u0430 \u0410\u0446\u0438\u043f\u0430\u043c\u043e\u043a\u0441 https:\/\/en.wikipedia.org\/wiki\/Acipimox https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8306591 &#8222;&#8230;After 3 days of acipimox treatment, fasting and 24-h plasma glucose and serum triglyceride concentrations were significantly reduced (p &lt; 0.05), but no longer after 4 weeks of treatment. 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