{"id":17182,"date":"2020-03-29T09:19:10","date_gmt":"2020-03-29T06:19:10","guid":{"rendered":"https:\/\/xenobg.com\/?p=17182"},"modified":"2020-03-29T09:22:06","modified_gmt":"2020-03-29T06:22:06","slug":"vitamin-b3-unsuspected-properties","status":"publish","type":"post","link":"https:\/\/xenobg.com\/en\/vitamin-b3-nepodozirani-svoistva\/","title":{"rendered":"B3-unsuspected properties"},"content":{"rendered":"

\u201eNiacinamide, one of the B vitamins, provides\nenergy to the mitochondrial system. Under stress and strong excitation, the cells\nexpel niacinamide NADH, but niacinamide itself has a calming anti-arousal\neffect and some of its actions resemble a hormone. Estrogen tends to\ninterfere with the formation of niacin from tryptophan. Tryptophan, instead of forming\nthe sedative niacin (pyridine carboxylic acid), can be directed to\nthe formation of the excitatory quinolinic acid (pyridine dicarboxylic acid\nacid) from polyunsaturated fats. The excitation must be in balance with\nenergy resources of the cell and niacinamide may play multiple protective\nroles by reducing excitation, increasing energy production and\nstabilises repair systems. The state of arousal and the type of energy\nmetabolism are critical factors in regulating cell function and\nsurvival. \u201e<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eGlucose and niacinamide work very closely with each other and with\nthyroid hormone in the maintenance and repair of cells and\ntissues. When one of these energy-producing factors is missing, changes in\ncell function - a sort of pre-inflammatory state - activate\ncorrective processes. \u201e<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eSome of the publications that claim resveratrol increases lifespan report that niacinamide has the opposite effect, suppressing Sir2, the longevity gene, and shortening the body's lifespan. To put their claims in context, it is useful to look at various experiments involving niacinamide treatment. It protects nerves, vascular cells, insulin-producing cells in the pancreas, and a number of other types of cells from cell death produced by lack of oxygen, excitotoxicity, endotoxin, and various stressors and toxins. (Niacinamide acts in many ways as a negative of resveratrol; for example, resveratrol interferes with the ability of beta cells to secrete insulin. \u201eIn some of the publications that claim resveratrol increases lifespan, niacinamide is reported to have the opposite effect, suppressing Sir2, the longevity gene, and shortening the body's lifespan. To put their claims in context, it is useful to look at various experiments involving niacinamide treatment. Niacinamide protects mitochondrial respiration from many age-related factors that can damage mitochondria and reduce energy production. Lipopolysaccharide, a bacterial endotoxin, increases the production of the free radical nitric oxide, leading to the secretion of inflammatory mediators and the suppression of mitochondrial energy production. These effects are blocked by niacinamide<\/a> .<\/em><\/strong><\/p>\n\n\n\n

\u201eNiacinamide, by reducing lipolysis, would be another\nanti-inflammatory agent that could help to interrupt the\ndegenerative processes initiated by radiation exposure.\u201c<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eThe \u201ctreatment\u201e for intracellular fatigue consists in normalizing the\nThyroid and steroid metabolism and eating a diet including freshet,\nmilk, eggs, liver, and gelatin, providing adequate calcium,\npotassium, sodium and magnesium and using supplements of niacinamide , aspirin and\ncarbon dioxide when necessary. \"<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eNiacinamide by lowering free fatty acids and\nregulating the redox system, promoting oxidation\nof sugar, is useful across the spectrum of metabolic degenerative\ndiseases.\u201c<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eThyroid hormone, vitamins A and E, niacinamide (to inhibit\nsystemic lipolysis), magnesium, calcium, progesterone, sugar, saturated fat\nand gelatin contribute in major ways to the prevention of inflammatory\nconditions that ultimately lead to amyloid diseases. Deficiency\nof degenerative brain diseases in high altitude populations\nis consistent with a protective role for carbon dioxide. \u201e<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eEliminating polyunsaturated fats from the diet is from\nessential if the eventual side effect will eventually be\nlimited. Aspirin can block many of the carcinogenic effects of PUFAs.\nSaturated fats have a variety of anti-inflammatory and anti-cancer\nactions. Some of these effects are direct, others result from blocking\ntoxic effects of PUFAs. Preservation of stored unsaturated fats by\ncirculation in the blood is beneficial, as it takes years for them to be eliminated\nfrom tissues after a change in diet. Niacinamide inhibits lipolysis.\nAvoiding overproduction of lipolytic adrenaline requires adequate\nthyroid hormone and dietary adjustment to minimize\nblood sugar fluctuations. \u201e<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eCharacteristics of stress metabolism include an increase in\nof stress hormones, lactate, ammonia, free fatty acids and synthesis of\nfat and a decrease in carbon dioxide. Factors that lower hormones\nstress hormones, increase carbon dioxide and help lower\ncirculating free fatty acids, lactate and ammonia, include vitamin B1\n(to increase CO2 and decrease lactate), niacinamide (to decrease\nfree fatty acids), sugar (to reduce cortisol, adrenaline and\nfree fatty acids), salt (to lower adrenaline), the hormone of\nthyroid (to increase CO2). Vitamins D, K, B6 and biotin are also\nclosely related to carbon dioxide metabolism. Biotin deficiency can\ncause aerobic glycolysis with increased fat synthesis.<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eThe stored PUFA released by stress or starvation is this slow\nmetabolism. Niacinamide helps lower free fatty acids and\ngood nutrition will allow the liver to slowly detoxify PUFA if it does not\nis flooded with large amounts of them. A small amount of coconut oil with each\nmeal will increase the ability to oxidize fats, giving a short time\nstop the antithyroid effect of PUFAs. Aspirin is another thing that reduces\nstress-related increase in free fatty acids, stimulating\nmetabolism.<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eThe amino acid theanine, found in tea, reportedly reduces\nthe amount of serotonin in the brain, possibly by reducing its synthesis and\nincreasing its breakdown. This appears to be the opposite of the processes in\nhibernation. Progesterone, thyroid and niacinamide (not nicotinic\nacid or inositol hexanicotinate) are other safe substances that\nhelp reduce serotonin formation and\/or accelerate its\n(Niacinamide appears to increase serotonin absorption.)<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eAs the blood becomes more concentrated, viscous and clotting\nat night (especially during long winter nights), the risk of heart attack or\nstroke is likely to be reduced by drinking orange juice at bedtime, for\nthin the blood and reduce adrenaline and free fatty acids,\nwhich contribute to an increased tendency to form clots in the morning.\n(Assanelli et al. Discuss the importance of adrenaline in sudden death in the morning\/\nwinter; Antoniades and Westmoreland show that the presence of glucose can\nabolish the major stimulants of clotting and bleeding.) Things to reduce\nstress-related coagulopathies: sugar and niacin to reduce to\nminimize the release of fatty acids, progesterone and thyroid, to\nto protect against estrogen and to avoid hypoglycemia (which increases\nadrenaline and free fatty acids and accelerates clotting), magnesium and\ngelatin (or glycine ) to protect against intracellular calcium\noverload and hypoxia, and vitamin E and salicylic acid to\nanti-inflammatory effects are essential nutrients that protect\ncirculatory system against clotting, bleeding, edema\u201e<\/em><\/strong><\/em><\/p>\n\n\n\n

\u201eFoods that support the patient well enough to\nmaintain healing while allowing energy to build up\nreserves, are also foods that do not affect the hormones, that do not\ncause false excitation of the tissues. Polyunsaturated fats directly\nstimulate stress hormones, activate excitatory signals\namino acids and directly excite cells, while saturated fats have\nopposite effect and are anti-inflammatory and also do not interfere with\nmitochondrial function. When we eat more carbohydrates than we can\noxidized, some of it will turn into saturated fat and omega-9 fats and they\nwill support mitochondrial energy production. The carbohydrates in\ndiet also help to reduce the mobilization of fatty acids from\nstorage; niacinamide and aspirin support this effect. \u201e<\/em><\/strong><\/em><\/p>\n\n\n\n

SCIENCE IS CLEAR AND RAY PETE HAS SHOWN THE AMAZING PROPERTIES OF NIACINAMIDE<\/a>. HE SHOWED THAT NIACINAMIDE:<\/em><\/strong><\/p>\n\n\n\n