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Витамин К МК4, течена формула, 100% усвоим Менакинон

Vitamin K2 MK4 – течна формула

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Продуктите са предназначени за употреба според указанията. Някои са преопаковани по стандартите на доставчика. Използвайте по собствена преценка.

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Алтернатива на Кинон от Idealabs

Vitamin K-MK4 – Подкрепете костите и сърцето си с мощната форма на витамин K2

Описание на продукта: Vitamin K-MK4 е висококачествена добавка, съдържаща менахинон-4 (MK-4) – една от най-биоактивните форми на витамин K2. Тази форма на витамин K2 играе ключова роля в поддържането на здравето на костите и сърдечно-съдовата система, като подпомага правилното използване на калция в организма.

Ключови ползи:

  1. Поддържане на здрави кости:

    • Активиране на остеокалцин: MK-4 е от съществено значение за активирането на остеокалцин – протеин, който свързва калция с костната матрица, укрепвайки костите и намалявайки риска от фрактури.

  2. Подобряване на сърдечно-съдовото здраве:

    • Предотвратяване на калцификацията на артериите: Чрез активиране на матрикс Gla протеин (MGP), MK-4 помага за предотвратяване на натрупването на калций в артериите, поддържайки тяхната еластичност и здраве.

  3. Подобрена бионаличност:

    • Бързо усвояване и действие: MK-4 се характеризира с бързо усвояване и действие в организма, което го прави ефективен избор за поддържане на оптимални нива на витамин K2.

Защо да изберете Vitamin K-MK4?

  • Висока чистота и качество: Нашият продукт съдържа чист менахинон-4, без добавени изкуствени съставки или консерванти.
  • Лесен за прием: Предлага се в удобна течна форма, която позволява лесно дозиране и бързо усвояване.
  • Подходящ за различни диети: Продуктът е без ГМО и глутен, подходящ за хора с различни хранителни предпочитания.

Начин на употреба:

  • Препоръчителна доза: Приемайте 1 капка (2 mg MK-4) дневно, разтворена в малко количество вода или директно под езика за по-бързо усвояване.
  • Съхранение: Съхранявайте на хладно и сухо място, далеч от пряка слънчева светлина.

Слогани за Vitamin K-MK4:

  • „Здрави кости, здраво сърце – всичко започва с Vitamin K-MK4“
  • ❤️ „Подкрепете сърцето и костите си с мощта на MK-4“
  • „Вашият съюзник за силни кости и здраво сърце“

Заключение: Vitamin K-MK4 е надежден избор за всеки, който иска да подкрепи здравето на костите и сърдечно-съдовата система. С доказаните ползи на менахинон-4, нашият продукт предлага ефективно решение за поддържане на оптимално здраве и жизненост.

https://lowtoxinforum.com/threads/kuinone-liquid-vitamin-k2-mk-4.9169/

референции:

General
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Vitamin E and K interactions–a 50-year-old problem. – PubMed – NCBI
Pleiotropic actions of vitamin K: protector of bone health and beyond? – PubMed – NCBI
Exocrine pancreatic secretion of phospholipid, menaquinone-4, and caveolin-1 in vivo. – PubMed – NCBI
Improvement of vitamin K status of breastfeeding infants with maternal supplement of vitamin K2 (MK40). – PubMed – NCBI
Antinociceptive effect induced by intraperitoneal administration of vitamin K2 (menatetrenone) in ICR mice. – PubMed – NCBI
Effect of dietary fat content on oral bioavailability of menatetrenone in humans. – PubMed – NCBI
Effect of food composition on vitamin K absorption in human volunteers. – PubMed – NCBI
Distribution of menaquinone-4, a therapeutic agent for osteoporosis, in bone and other tissues of rats. – PubMed – NCBI

Bone Health
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Low-dose menaquinone-4 improves γ-carboxylation of osteocalcin in young males: a non-placebo-controlled dose-response study. – PubMed – NCBI
Vitamin K2 improves femoral bone strength without altering bone mineral density in gastrectomized rats. – PubMed – NCBI
Vitamin K₂ therapy for postmenopausal osteoporosis. – PubMed – NCBI
Vitamin K-dependent carboxylation of osteocalcin affects the efficacy of teriparatide (PTH(1-34)) for skeletal repair. – PubMed – NCBI
Menatetrenone versus alfacalcidol in the treatment of Chinese postmenopausal women with osteoporosis: a multicenter, randomized, double-blinded, do… – PubMed – NCBI
Effects of vitamin K in postmenopausal women: mini review. – PubMed – NCBI
Menatetrenone for the treatment of osteoporosis. – PubMed – NCBI
Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone. – PubMed – NCBI
Amelioration of pregnancy-associated osteoporosis after treatment with vitamin K₂: a report of four patients. – PubMed – NCBI
Clinical results of alendronate monotherapy and combined therapy with menatetrenone (VitK₂) in postmenopausal RA patients. – PubMed – NCBI
Bridging the gap between osteoporosis and osteonecrosis of the jaw: preventing and treating BRONJ with MK4. – PubMed – NCBI
Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral de… – PubMed – NCBI
The prevention of hip fracture with menatetrenone and risedronate plus calcium supplementation in elderly patients with Alzheimer disease: a random… – PubMed – NCBI
Effect of vitamin K2 on cortical and cancellous bone mass and hepatic lipids in rats with combined methionine-choline deficiency. – PubMed – NCBI
Effect of GGCX gene polymorphism on the responses of serum undercarboxylated osteocalcin and bone turnover markers after treatment with vitamin K2 … – PubMed – NCBI
Effects of long-term vitamin K(1) (phylloquinone) or vitamin K(2) (menaquinone-4) supplementation on body composition and serum parameters in rats. – PubMed – NCBI
Vitamin K₂ alters bone metabolism markers in hemodialysis patients with a low serum parathyroid hormone level. – PubMed – NCBI
Effects of vitamin K2 on cortical and cancellous bone mass, cortical osteocyte and lacunar system, and porosity in sciatic neurectomized rats. – PubMed – NCBI
Vitamin K2 promotes bone healing in a rat femoral osteotomy model with or without glucocorticoid treatment. – PubMed – NCBI
Effects of combination treatment with alendronate and vitamin K(2) on bone mineral density and strength in ovariectomized mice. – PubMed – NCBI
Prevention of hip fractures by exposure to sunlight and pharmacotherapy in patients with Alzheimer’s disease. – PubMed – NCBI
Vitamin K to prevent fractures in older women: systematic review and economic evaluation. – PubMed – NCBI
Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -indep… – PubMed – NCBI
Efficacy of menatetrenone (vitamin K2) against non-vertebral and hip fractures in patients with neurological diseases: meta-analysis of three rando… – PubMed – NCBI
Comparison of the effect of vitamin K(2) and risedronate on trabecular bone in glucocorticoid-treated rats: a bone histomorphometry study. – PubMed – NCBI
Collagen-related abnormalities, reduction in bone quality, and effects of menatetrenone in rats with a congenital ascorbic acid deficiency. – PubMed – NCBI
Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate. – PubMed – NCBI
Short-term menatetrenone therapy increases gamma-carboxylation of osteocalcin with a moderate increase of bone turnover in postmenopausal osteoporo… – PubMed – NCBI
Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North Am… – PubMed – NCBI
Randomized controlled study on the prevention of osteoporotic fractures (OF study): a phase IV clinical study of 15-mg menatetrenone capsules. – PubMed – NCBI
Vitamin K2, a gamma-carboxylating factor of gla-proteins, normalizes the bone crystal nucleation impaired by Mg-insufficiency. – PubMed – NCBI
[Treatment of primary osteoporosis with vitamin K2]. – PubMed – NCBI
[Vitamin K metabolism. Menaquinone-4 (MK-4) formation from ingested VK analogues and its potent relation to bone function]. – PubMed – NCBI
Vitamin K2 induces phosphorylation of protein kinase A and expression of novel target genes in osteoblastic cells. – PubMed – NCBI
Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene. – PubMed – NCBI
Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. – PubMed – NCBI
Menatetrenone (vitamin K2) and bone quality in the treatment of postmenopausal osteoporosis. – PubMed – NCBI
Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a b… – PubMed – NCBI
Infrared analysis of bones in magnesium-deficient rats treated with vitamin K2. – PubMed – NCBI
[Active vitamin D and vitamin K as therapeutic agents for osteoporosis]. – PubMed – NCBI
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[Therapeutic approaches for diabetic osteopahty]. – PubMed – NCBI
Vitamin K2 treatment for postmenopausal osteoporosis in Indonesia. – PubMed – NCBI
Geranylgeranylacetone inhibits formation and function of human osteoclasts and prevents bone loss in tail-suspended rats and ovariectomized rats. – PubMed – NCBI
Comparative effects of vitamin K and vitamin D supplementation on calcium balance in young rats fed normal or low calcium diets. – PubMed – NCBI
[The interplay of magnesium and vitamin K2 on bone mineralization]. – PubMed – NCBI
[Vitamin K2 and bone quality]. – PubMed – NCBI
[Vitamin K2 (menatetrenone) and bone quality]. – PubMed – NCBI
Effects of vitamin K2 administration on calcium balance and bone mass in young rats fed normal or low calcium diet. – PubMed – NCBI
Menatetrenone rescues bone loss by improving osteoblast dysfunction in rats immobilized by sciatic neurectomy. – PubMed – NCBI
RETRACTED: Menatetrenone and vitamin D2 with calcium supplements prevent nonvertebral fracture in elderly women with Alzheimer’s disease. – PubMed – NCBI
Vitamin K2 inhibits glucocorticoid-induced bone loss partly by preventing the reduction of osteoprotegerin (OPG). – PubMed – NCBI
Effects of vitamin K2 (menatetrenone) and alendronate on bone mineral density and bone strength in rats fed a low-magnesium diet. – PubMed – NCBI
Histochemical evaluation for the biological effect of menatetrenone on metaphyseal trabeculae of ovariectomized rats. – PubMed – NCBI
Effects of vitamin K2 in hemodialysis patients with low serum parathyroid hormone levels. – PubMed – NCBI
Vitamin K2 and geranylgeraniol, its side chain component, inhibited osteoclast formation in a different manner. – PubMed – NCBI
Protective effect of vitamins K2 and D3 on prednisolone-induced loss of bone mineral density in the lumbar spine. – PubMed – NCBI
Menatetrenone ameliorates reduction in bone mineral density and bone strength in sciatic neurectomized rats. – PubMed – NCBI
Treatment with vitamin D3 and/or vitamin K2 for postmenopausal osteoporosis. – PubMed – NCBI
Menatetrenone (vitamin K2) acts directly on circulating human osteoclast precursors. – PubMed – NCBI
High serum levels of menatetrenone in male patients with ossification of the posterior longitudinal ligament. – PubMed – NCBI
Effect of menatetrenone (vitamin K2) treatment on bone loss in patients with anorexia nervosa. – PubMed – NCBI
Effect of vitamin K2 on cortical and cancellous bones in orchidectomized and/or sciatic neurectomized rats. – PubMed – NCBI
Vitamin K stimulates osteoblastogenesis and inhibits osteoclastogenesis in human bone marrow cell culture. – PubMed – NCBI
Effect of vitamin K2 on cortical and cancellous bones in orchidectomized young rats. – PubMed – NCBI
Pharmacodynamics of menatetrenone and effects on bone metabolism in continuous ambulatory peritoneal dialysis patients. – PubMed – NCBI
Vitamin K2 (menatetrenone) inhibits bone loss induced by prednisolone partly through enhancement of bone formation in rats. – PubMed – NCBI
Menatetrenone prevents osteoblast dysfunction in unilateral sciatic neurectomized rats. – PubMed – NCBI
[Effect of menatetrenone (V.K2) on bone mineral density and bone strength in Ca/Mg deficient rats]. – PubMed – NCBI
Time-dependent effects of vitamin K2 (menatetrenone) on bone metabolism in postmenopausal women. – PubMed – NCBI
Maintenance of trabecular structure and bone volume by vitamin K(2) in mature rats with long-term tail suspension. – PubMed – NCBI
Amelioration of osteoporosis by menatetrenone in elderly female Parkinson’s disease patients with vitamin D deficiency. – PubMed – NCBI
A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis. – PubMed – NCBI
Vitamin K2 (menatetrenone) for bone loss in patients with cirrhosis of the liver. – PubMed – NCBI
Effects of phenytoin and/or vitamin K2 (menatetrenone) on bone mineral density in the tibiae of growing rats – PubMed
Effects of vitamin K2 (menatetrenone) on calcium balance in ovariectomized rats – PubMed
Efficacy and safety of Menatetrenone-4 postmenopausal Thai women – PubMed
Vitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiency – PubMed
Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate – PubMed
Effects of vitamin K on calcium and bone metabolism – PubMed
Inverse correlation between the changes of lumbar bone mineral density and serum undercarboxylated osteocalcin after vitamin K2 (menatetrenone) treatment in children treated with glucocorticoid and alfacalcidol – PubMed
Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis – PubMed
[Effects of vitamin K2 administration in the patients with severely motor and intellectual disabilities: assessment of bone metabolic marker and bone mineral density] – PubMed
Vitamin K(2) inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in murine bone marrow cell cultures – PubMed
Effect of vitamin K2 on three-dimensional trabecular microarchitecture in ovariectomized rats – PubMed
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis – PubMed
Short-term effect of vitamin K administration on prednisolone-induced loss of bone mineral density in patients with chronic glomerulonephritis – PubMed
Menatetrenone plus alfacalcidol treatment for bone problems in eight children with skeletal unloading – PubMed
[Vitamin K2 (menatetrenone) treatment increased bone strength in rats given low-calcium diets] – PubMed
Inhibitory effect of vitamin K2 (menatetrenone) on bone resorption in ovariectomized rats: a histomorphometric and dual energy X-ray absorptiometric study – PubMed
Use of vitamin K2 (menatetrenone) and 1,25-dihydroxyvitamin D3 in the prevention of bone loss induced by leuprolide – PubMed
A longitudinal study of the effect of vitamin K2 on bone mineral density in postmenopausal women a comparative study with vitamin D3 and estrogen-progestin therapy – PubMed
[Effects of a vitamin K2 preparation in severely handicapped patients complicated by osteopenia] – PubMed
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Inflammation
http://www.ncbi.nlm.nih.gov/pubmed/8240383
http://www.ncbi.nlm.nih.gov/pubmed/8511981

Cardiovascular disease (CVD)
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Diabetes
http://www.ncbi.nlm.nih.gov/pubmed/21136047
http://www.ncbi.nlm.nih.gov/pubmed/11325029

Kidney Health
http://www.ncbi.nlm.nih.gov/pubmed/22080166

Cancer
http://www.ncbi.nlm.nih.gov/pubmed/23225445
http://www.ncbi.nlm.nih.gov/pubmed/23191943
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Neurological Health
http://www.ncbi.nlm.nih.gov/pubmed/24108469
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Testosterone
http://www.ncbi.nlm.nih.gov/pubmed/21914161
http://www.ncbi.nlm.nih.gov/pubmed/21894328

Estrogen
http://www.ncbi.nlm.nih.gov/pubmed/15763078

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