B3 - the unsuspected properties

„Niacinamide, one of the B vitamins, provides energy to the mitochondrial system. Under stress and strong excitation, the cells expel niacinamide NADH, but niacinamide itself has a calming anti-arousal effect and some of its actions resemble a hormone. Estrogen tends to interfere with the formation of niacin from tryptophan. Tryptophan, instead of forming the sedative niacin (pyridine carboxylic acid), can be directed to the formation of the excitatory quinolinic acid (pyridine dicarboxylic acid acid) from polyunsaturated fats. The excitation must be in balance with energy resources of the cell and niacinamide may play multiple protective roles by reducing excitation, increasing energy production and stabilises repair systems. The state of arousal and the type of energy metabolism are critical factors in regulating cell function and survival. „

„Glucose and niacinamide work very closely with each other and with thyroid hormone in the maintenance and repair of cells and tissues. When one of these energy-producing factors is missing, changes in cell function - a sort of pre-inflammatory state - activate corrective processes. „

„Some of the publications that claim resveratrol increases lifespan report that niacinamide has the opposite effect, suppressing Sir2, the longevity gene, and shortening the body's lifespan. To put their claims in context, it is useful to look at various experiments involving niacinamide treatment. It protects nerves, vascular cells, insulin-producing cells in the pancreas, and a number of other types of cells from cell death produced by lack of oxygen, excitotoxicity, endotoxin, and various stressors and toxins. (Niacinamide acts in many ways as a negative of resveratrol; for example, resveratrol interferes with the ability of beta cells to secrete insulin. „In some of the publications that claim resveratrol increases lifespan, niacinamide is reported to have the opposite effect, suppressing Sir2, the longevity gene, and shortening the body's lifespan. To put their claims in context, it is useful to look at various experiments involving niacinamide treatment. Niacinamide protects mitochondrial respiration from many age-related factors that can damage mitochondria and reduce energy production. Lipopolysaccharide, a bacterial endotoxin, increases the production of the free radical nitric oxide, leading to the secretion of inflammatory mediators and the suppression of mitochondrial energy production. These effects are blocked by niacinamide .

„Niacinamide, by reducing lipolysis, would be another anti-inflammatory agent that could help to interrupt the degenerative processes initiated by radiation exposure.“

„The “treatment„ for intracellular fatigue consists in normalizing the Thyroid and steroid metabolism and eating a diet including freshet, milk, eggs, liver, and gelatin, providing adequate calcium, potassium, sodium and magnesium and using supplements of niacinamide , aspirin and carbon dioxide when necessary. "

„Niacinamide by lowering free fatty acids and regulating the redox system, promoting oxidation of sugar, is useful across the spectrum of metabolic degenerative diseases.“

„Thyroid hormone, vitamins A and E, niacinamide (to inhibit systemic lipolysis), magnesium, calcium, progesterone, sugar, saturated fat and gelatin contribute in major ways to the prevention of inflammatory conditions that ultimately lead to amyloid diseases. Deficiency of degenerative brain diseases in high altitude populations is consistent with a protective role for carbon dioxide. „

„Eliminating polyunsaturated fats from the diet is from essential if the eventual side effect will eventually be limited. Aspirin can block many of the carcinogenic effects of PUFAs. Saturated fats have a variety of anti-inflammatory and anti-cancer actions. Some of these effects are direct, others result from blocking toxic effects of PUFAs. Preservation of stored unsaturated fats by circulation in the blood is beneficial, as it takes years for them to be eliminated from tissues after a change in diet. Niacinamide inhibits lipolysis. Avoiding overproduction of lipolytic adrenaline requires adequate thyroid hormone and dietary adjustment to minimize blood sugar fluctuations. „

„Characteristics of stress metabolism include an increase in of stress hormones, lactate, ammonia, free fatty acids and synthesis of fat and a decrease in carbon dioxide. Factors that lower hormones stress hormones, increase carbon dioxide and help lower circulating free fatty acids, lactate and ammonia, include vitamin B1 (to increase CO2 and decrease lactate), niacinamide (to decrease free fatty acids), sugar (to reduce cortisol, adrenaline and free fatty acids), salt (to lower adrenaline), the hormone of thyroid (to increase CO2). Vitamins D, K, B6 and biotin are also closely related to carbon dioxide metabolism. Biotin deficiency can cause aerobic glycolysis with increased fat synthesis.

„The stored PUFA released by stress or starvation is this slow metabolism. Niacinamide helps lower free fatty acids and good nutrition will allow the liver to slowly detoxify PUFA if it does not is flooded with large amounts of them. A small amount of coconut oil with each meal will increase the ability to oxidize fats, giving a short time stop the antithyroid effect of PUFAs. Aspirin is another thing that reduces stress-related increase in free fatty acids, stimulating metabolism.

„The amino acid theanine, found in tea, reportedly reduces the amount of serotonin in the brain, possibly by reducing its synthesis and increasing its breakdown. This appears to be the opposite of the processes in hibernation. Progesterone, thyroid and niacinamide (not nicotinic acid or inositol hexanicotinate) are other safe substances that help reduce serotonin formation and/or accelerate its (Niacinamide appears to increase serotonin absorption.)

„As the blood becomes more concentrated, viscous and clotting at night (especially during long winter nights), the risk of heart attack or stroke is likely to be reduced by drinking orange juice at bedtime, for thin the blood and reduce adrenaline and free fatty acids, which contribute to an increased tendency to form clots in the morning. (Assanelli et al. Discuss the importance of adrenaline in sudden death in the morning/ winter; Antoniades and Westmoreland show that the presence of glucose can abolish the major stimulants of clotting and bleeding.) Things to reduce stress-related coagulopathies: sugar and niacin to reduce to minimize the release of fatty acids, progesterone and thyroid, to to protect against estrogen and to avoid hypoglycemia (which increases adrenaline and free fatty acids and accelerates clotting), magnesium and gelatin (or glycine ) to protect against intracellular calcium overload and hypoxia, and vitamin E and salicylic acid to anti-inflammatory effects are essential nutrients that protect circulatory system against clotting, bleeding, edema„

„Foods that support the patient well enough to maintain healing while allowing energy to build up reserves, are also foods that do not affect the hormones, that do not cause false excitation of the tissues. Polyunsaturated fats directly stimulate stress hormones, activate excitatory signals amino acids and directly excite cells, while saturated fats have opposite effect and are anti-inflammatory and also do not interfere with mitochondrial function. When we eat more carbohydrates than we can oxidized, some of it will turn into saturated fat and omega-9 fats and they will support mitochondrial energy production. The carbohydrates in diet also help to reduce the mobilization of fatty acids from storage; niacinamide and aspirin support this effect. „

SCIENCE IS CLEAR AND RAY PETE HAS SHOWN THE AMAZING PROPERTIES OF NIACINAMIDE. HE SHOWED THAT NIACINAMIDE: